He first published an article about the homeopathic approach in a German-language medical journal in 1796. Following a series of further essays, he published in 1810 "Organon of the Rational Art of Healing", followed over the years by four further editions entitled The Organon of the Healing Art, the first systematic treatise and containing all his detailed instructions on the subject. A 6th Organon edition, unpublished during his lifetime, and dating from February 1842, was only published many years after his death. It consisted of a 5th Organon containing extensive handwritten annotations. The Organon is widely regarded as a remodelled form of an essay he published in 1806 called "The Medicine of Experience", which had been published in Hufeland's Journal. Of the Organon, Robert Ellis Dudgeon states it "was an amplification and extension of his "Medicine of Experience", worked up with greater care, and put into a more methodical and aphoristic form, after the model of the Hippocratic writings."