In 1958, Frank married his first wife Eleanor, who was 15 years his senior. Perry and Eleanor collaborated on many screen projects, including screenwriting the Academy Award-nominated 1962 "David & Lisa". They divorced in 1971 on grounds of incompatibility. She later wrote the book Blue Pages about her relationship with Frank. The union produced no children. Eleanor Perry died of cancer a decade later, at age 66. In 1977, Perry married his second wife, Barbara Goldsmith, founding Editor of New York magazine and book author (Little Gloria … Happy at Last), whom he divorced in 1992. Soon after, he married his Aspen ski instructor, 22-year-younger Virginia Brush Ford, on June 15, 1992. His sister is pastor Mary Christine Perry, the wife of pastor Maurice Keith Hudson and mother of Singers Katy Perry and David Hudson.