Tanishaa got her first break in Bollywood with her film, Sssshhh.... Her Tamil movie Unnale Unnale, opposite Vinay Rai was successful at the box office and got her a nomination at Vijay Awards for Best Debut Actress. In 2006, she played the female lead character of Nikkita Bakshi aka Nikki, in Neal N Nikki, opposite Uday Chopra. She was also seen in movies such as Popcorn Khao! Mast Ho Jao, Sarkar,Tango Charlie and many more.