Shortly after her marriage, Jenkins went to Yaddo, the artists' colony in Saratoga Springs, New York, to work on her next screenplay that would eventually become 2007's The Savages. For this tragicomedy about a dysfunctional family dealing with the aftershocks of its patriarch's elderly dementia, Jenkins took inspiration from her experiences with her grandmother and father, both of whom were in nursing homes with dementia. Jenkins' father, who was much older than her mother, first needed care when his daughter was in her 30s. Additionally, Jenkins built upon her theater work at The New Group, departing from her previously straight dramas to something far more absurd. The film layers a bright, doll-like color palette upon a bleak and often morbid story, relying on the Savage wit of her screenplay to tie the film together.