In 2011, Case, along with Ted Leonsis and Donn Davis, launched the $450 million Revolution Growth fund. The fund's Investments to date include Bigcommerce, CustomInk, Echo360, FedBid, Handy, Lolly Wolly Doodle, Optoro, Resonate, Revolution Foods, Sweetgreen, Sparefoot, Bedrock Manufacturing, LDiscovery, Interactions, Cava, DraftKings and Sportradar. In 2013, he launched the Revolution Ventures fund with Tige Savage and David Golden. Revolution Ventures has invested in BenchPrep, Booker, Busbud, Framebridge, Homesnap, Insikt, OrderUp, RunKeeper, MemberSuite, and PolicyGenius.