Ticotin's film work includes: Critical Condition (1987) as Rachel Atwood, Where the Day Takes You (1992) as Officer Landers, Falling Down (1993) as Detective Sandra Torres, Total Recall (1990) as Melina alongside Arnold Schwarzenegger and Sharon Stone, First Time Felon (1997) as Mcbride alongside Omar Epps, and Con Air (1997) alongside Nicolas Cage, in which she earned an ALMA Award for her role as prison guard Sally Bishop. In 1995, she played the role of Doña Inez, the Mexican mother of Don Juan in the tongue-in-cheek romantic comedy Don Juan Demarco, with Johnny Depp playing the title role.