Nick Damici grew up in Hell's Kitchen in the 1960s and early 1970s. His father was a bartender, and Damici would occasionally tend bar at the age of 12.He is of mixed Italian and Canarian descent.
Damici's mentor is Michael Moriarty, who encouraged him to write scripts. Acting remains his primary love; in an interview, he described writing as a "lonely, thankless job". After he tired of supporting roles on television shows, he decided to write starring roles for himself. Damici and Jim Mickle have worked together since 2001 and have collaborated on four films: Mulberry Street, Stake Land, We Are What We Are, and Cold in July. Damici originally wrote Stake Land to be a web series, but Larry Fessenden was enthusiastic about making it into a feature film. In February 2013, he was cast in Adrian Garcia Bogliano's Late Phases.
