Birbiglia made his directorial debut with Sleepwalk with Me, based on his one-man show and which he wrote, directed, and starred in. The film premiered at the 2012 Sundance Film Festival and won the NEXT Audience Award. It was selected in the "Festival Favorites" category at the South by Southwest film festival in Austin, Texas and also appeared in the Nantucket Film Festival where it won the award for best writer/director. The film was produced by Jacob Jaffke and This American Life's Ira Glass and stars Birbiglia, Lauren Ambrose, Carol Kane, James Rebhorn, and Cristin Milioti and has cameos by Glass, Kristen Schaal, Wyatt Cenac, David Wain, Jessi Klein, John Lutz and Marc Maron.