Main married Stanley LeFevre Krebs, who died in 1935. By her accounts, the marriage was happy, but not particularly close. Her biographer, Michelle Vogel, quotes a late interview in which the Actress related: "Dr. Krebs wasn't a very practical man. I didn't figure on having to run the show, I kinda tired of it after a few years. We pretty much went our own ways but we was still in the eyes of the law, man and wife". Other sources indicate Main was, in actuality, devoted to her husband long after his death in 1935.