Llong became a member of the Franciscans and she founded both a house to care for prostitutes in 1526 and a hospital for ill people. Llong established the hospital of Santa Maria del Popolo in 1519. Llong wanted to go on a pilgrimage but she had a vision that revealed that she should create a women's convent called "Santa Maria in Gerasalamme" and she wanted to re-establish the original concepts of being simple and humble in addition to poorness of spirit and adherence to the austerities of Saint Francis of Assisi and Saint Clare of Assisi. This re-establishment followed the lead that Matteo da Bascio had set when he founded the order of the Capuchin monks.