Leaving high school before graduating, he started a small band which traveled to Mexico. He returned months later to pursue an acting career, but continued working full-time as a musician. He played banjo and guitar for big bands, including the Henry Halstead Orchestra. He recorded one of the earliest Vitaphone movie shorts called Carnival Night in Paris (Warner Brothers, 1927). Ayres wrote, "I was a member of Henry Halstead's orchestra in 1927 at the Mission Beach Ballroom in San Diego, California for the summer. My instruments were tenor banjo, long-neck banjo and guitar. After a hiatus, I rejoined Mr. Halstead with a new group, including Phil Harris, on New Year's Eve the same year for the opening night of the Beverly Wilshire Hotel, a memorable occasion." He left a national tour to pursue a career as an actor full-time.