In 2006, Cohen was included in the Masters of Horror TV anthology, which also included – but was not limited to – Writers and Directors as diverse as Dario Argento, Clive Barker, John Carpenter, Richard Chizmar, Don Coscarelli, Wes Craven, David Cronenberg, Joe Dante, Guillermo del Toro, Ernest Dickerson, Stuart Gordon, James Gunn, Sam Hamm, Tom Holland, Tobe Hooper, Lloyd Kaufman, Mary Lambert, John Landis, Joe R. Lansdale, Bentley Little, H.P. Lovecraft, Joe Lynch, william Lustig, Peter Medak, Lucky McKee, Kat O' Shea, Robert Rodriguez, Eli Roth, David Schow, and Tim Sullivan. It was created by Mick Garris for the Showtime cable network. Cohen's contribution was the segment Pick Me Up, based on a short story by David Schow, who also wrote the teleplay. It stars Fairuza Balk and Cohen regulars Laurene Landon and Michael Moriarty. Pick Me Up is the story of woman traveling on a bus that has broken down along a stretch of lonely two-lane blacktop. Enter two serial killers: Wheeler (Moriarty), a driver who picks up hitchhikers with the sole intent of killing them – and – Walker (Warren Kole), a hitchhiker who accepts lifts in order to find his victims. The two killers pair up and inventively murder all the passengers on the bus, save for Stacia (Balk), who has since gone her own way. Stacia eventually winds up in the middle of a serial killer turf war, a war over which killer will get her first. Pick Me Up signaled a brief return to the director's chair for Cohen.