Kirkpatrick was born in Monroe, Louisiana, and spent the formative years of his life in Baton Rouge. Kirkpatrick attended a performing arts school and started out as an actor. Formerly, he performed in the SAK Comedy Lab improvisational theater in Orlando, Florida. He is an alumnus of Baton Rouge Magnet High School in Baton Rouge, Louisiana. Kirkpatrick attended the University of Southern California, graduating in 1988. His career pursuits eventually landed him on the streets of Walt Disney World's EPCOT Center, where he performed improvisational audience-participation street theater. As his artistic focus turned to writing, he was accepted to the USC School of Cinema-Television's Filmic Writing Program, where he won the Robert Riskin Screenwriting Award and the Jack Nicholson Screenwriting Awards.