Upon completing his studies Tiran joined the Cameri Theater in Tel Aviv. Among his parts were Eilif in Mother Courage, Franz Jägerstätter in Yehoshua Sobol's Eye Witness (directed by Paulus Manker), Nicolah in Caviar and Lentils, the title role in Hamlet directed by Omri Nitzan, Christian in Festen, and Mozart in Amadeus. In March 2007, Itay received rave reviews from audiences and media in Washington DC for his performance as Hamlet in the Tel Aviv Cameri Theater production's world tour. The "Israeli Hamlet" performed in Shanghai, Cleveland, Gdańsk, Bucharest and Moscow. In 2010, Itay played Kittel in Yehoshua Sobol's Ghetto followed by a remarkable directing debut with Georg Büchner's Woyzeck in which he also played the title role. Tiran's Woyzeck was embraced by the critiques making him a theater Director to reckon with. In late 2011 the Cameri Theater's production of Cabaret featured a dark, scary MC portrayed by Itay Tiran which ultimately won him the Best Actor Award at the 2011 Israeli Theater Awards. In July 2012 the Cameri Theater staged a special project, william Shakespeare's Richard II and Richard III, directed by Arthur Kogan with Tiran in both Title Roles. The project was a huge critical and commercial success. Tiran's virtuosic performance abilities were awarded at the 2012 Israeli Theater Awards when he won Best Actor for Richard III. The Cameri's "Richards" Project won 7 Awards including Best Director, Best Supporting Actor, Best Play. In the summer of 2013 Tiran adapted the book "Little Man,What Now?" by Hans Fallada. The play, beautifully directed, earned him huge critical acclaim as a Theater Director, the paper Haaretz even called Tiran the Laurence Olivier of Israeli Theater. Tiran's Woyzeck went to the Büchner Festival in Wiesbaden/Germany in the spring of 2013, opening to rave reviews. It was announced that Tiran is to play the title Role in the play Cyrano De Bergerac by Edmond Rostand in late 2013.