George Argyros was born in Detroit, Michigan, and raised in Pasadena, California. Argyros is a second-generation American citizen; his grandparents emigrated from Greece. Argyros graduated from Chapman University in 1959 with a major in Business and Economics. He later served on the board of trustees of that university, including chairman of the board from 1976 to 2001. The Chapman University, Argyros School of Business and Economics is named in his honor.