After the success of Dracula, Manners worked for several years as a romantic leading man, and was most often seen in a tuxedo in romantic comedies and light dramas. The Last FLIGHT (1931), a Lost Generation celebration of the high life in Paris, and Karl Freund's The Mummy (1932) with Boris Karloff were two standouts. But by 1936 he had grown bored with Hollywood, and abandoned his film career. He reportedly never acclimated to Hollywood, which he found to be "a false place". Although he was among the first group of actors to join the fledgling Screen Actors Guild in 1933, he returned to New York City, but he moved back to California three years later. Manners grew increasingly frustrated with his roles in Hollywood and with his film career in general, despite all its successes. Following his work on three films released in 1936—Hearts in Bondage, A Woman Rebels, and Lucky Fugitives—he left the studios and retired from film work. He did, however, continue to perform regularly on stage for another 17 years, appearing in various productions on tour, in summer stock, and on Broadway, including the ill-fated 1946 play Hidden Horizon. In 1953, Manners retired from acting entirely.