Darlene married Robert Cates, a U.S. Marine, on January 11, 1963. She had one daughter, Sheri Ann (b. 1966), and two sons, Mark (b. 1967) and Chris (b. 1971). She had four grandchildren and lived in the Dallas suburbs. In 1992, she received her high school diploma via correspondence courses. In 2012, Cates had lost 240 pounds after a series of 2010 health issues kept her hospitalized for nearly a year, and she expressed a Desire to resume her acting career.