After graduating from high school, Kingsolver attended DePauw University in Greencastle, Indiana, on a music scholarship, studying classical piano. Eventually, however, she changed her major to biology when she realized that "classical Pianists compete for six job openings a year, and the rest of [them] get to play 'Blue Moon' in a hotel lobby". She was involved in activism on her campus, and took part in protests against the Vietnam war. She graduated Phi Beta Kappa with a Bachelor of Science in 1977, and moved to France for a year before settling in Tucson, Arizona, where she lived for much of the next two decades. In 1980, she enrolled in graduate school at the University of Arizona, where she earned a master's degree in ecology and evolutionary biology.