Keddie had guest roles early in her career in various television dramas, including her first roles in Five Mile Creek (1985), Fortress (1986) and Janus (1994). She played the role of Marriane Sheridan in Blue Heelers (season 3, episode 21) airing on 18 June 1996 and Good Guys, Bad Guys (1997). From 1997 to 1998, she came to the attention of senior network television producers, appearing in State Coroner. Following this, she had a recurring role in Stingers from 2000 to 2004.