Kazembek started his career as a Linguist by translating Christian books into Oriental languages. In addition to the languages he already knew, he learned French, German and Tatar. In 1825, he received an invitation to complete his bachelor's degree in London. However the Russian government refused to let him out of the country, fearing that Kazembek would choose to stay and work in England upon graduation. Instead by Imperial decree he was appointed as a Teacher of the Tatar language in Omsk, thus being held away from his academic instructors. He never made it to Omsk as, while staying in Kazan due to an illness, Kazembek met Historian Karl Fuchs and was invited by him to pass an academic test to determine Kazembek's eligibility to teach Arabic and Persian at Kazan University. The test was passed and Kazembek was hired as a senior Teacher. In 1828, he was chosen to be a member of the Royal Asiatic Society and became head of the newly established Faculty of Turkic languages at Kazan University. In 1831, he attained a master's degree after writing an academic essay called Views on the History and Vocabulary of the Arabic Language (in Persian). In 1835 he was admitted to the Russian Academy of Sciences as a Corresponding Member. In 1837, he earned a Ph.D. degree at Kazan University. In 1839, he wrote a detailed work called Grammar of the Turco-Tatar language (at that time, most Turkic languages were regarded as dialects of one single language unit often referred to as 'Tatar' or 'Turco-Tatar'), where he compared Ottoman Turkish, Azeri and various dialects of Tatar in terms of their phonology, morphology, and syntax and for which he received the Demidov Prize. The second edition of this book was published in 1846 and incorporated the author's latest research in the field. It became popular in Western Europe, being the richest academic source on the Turkic languages at that time, and was used in universities as a primary reference book until 1921, when Jean Deny published his Grammar of the Turkish language (Ottoman dialect).